Worldwide blockchain revenues fell 35% between 2018 and 2020. Global tech market advisory firm ABI Research calculated the potential loss to hit US$2.8 billion. The 2018 crypto winter wiped 80% of the total aggregate market cap, and since then, more than 2,000 cryptocurrencies have collapsed.

Early commercial success, mainly across select use cases such as health professional credentialing, medical billing management, personal health records (PHR), and pharma supply chain track-and-trace, will help this market cross $500 million by 2022 at a compound annual growth rate (CARG) of 61.40%. While payback may not be achieved for every dollar invested by 2022, a breakeven stage is expected.